{"id":9580,"date":"2021-10-13T12:24:28","date_gmt":"2021-10-13T06:54:28","guid":{"rendered":"https:\/\/www.practicemock.com\/blog\/?p=9580"},"modified":"2021-10-13T12:24:28","modified_gmt":"2021-10-13T06:54:28","slug":"the-hindu-editorial-vocabulary-oct-13-2021-day-159","status":"publish","type":"post","link":"https:\/\/www.practicemock.com\/blog\/the-hindu-editorial-vocabulary-oct-13-2021-day-159\/","title":{"rendered":"The Hindu Editorial Vocabulary\u2013 Oct 13, 2021; Day 159"},"content":{"rendered":"\n<figure class=\"wp-block-table\"><table><tbody><tr><td>Difficult Word\/ Phrase<\/td><td>Contextual Sense<\/td><\/tr><tr><td>Jab&nbsp;<\/td><td>Taking a vaccine as a precaution against contracting a disease<\/td><\/tr><tr><td>Immunogenicity&nbsp;<\/td><td>relating to or producing an immune response<\/td><\/tr><tr><td>Nod&nbsp;<\/td><td>A sign of assent<\/td><\/tr><tr><td>Realm&nbsp;<\/td><td>an area of activity<\/td><\/tr><tr><td>Regimens&nbsp;<\/td><td>(medicine) a systematic plan for therapy (often including diet)<\/td><\/tr><tr><td>Size down&nbsp;<\/td><td>to gradate or arrange from larger to smaller<\/td><\/tr><tr><td>Physiological&nbsp;<\/td><td>Of or consistent with an organism&#8217;s normal functioning<\/td><\/tr><tr><td>Empirical&nbsp;<\/td><td>Derived from experiment and observation rather than theory<\/td><\/tr><tr><td>Cohort&nbsp;<\/td><td>a group of individuals having a statistical factor (such as age or class membership) in common in a demographic study<\/td><\/tr><tr><td>Cornerstone&nbsp;<\/td><td>The fundamental assumptions from which something is begun, developed, calculated or explained<\/td><\/tr><\/tbody><\/table><\/figure>\n\n\n\n<figure class=\"wp-block-image size-large\"><a href=\"https:\/\/www.practicemock.com\/exams\/banking\/ibps-rrb-office-assistant\/?refcode=2896&amp;utm_source=Blog_The+Hindu+Editorial+Vocabulary%E2%80%93+Oct+13%2C+2021%3B+Day+159_131021_RRBOAM&amp;utm_medium=Link&amp;utm_campaign=RRROAM\"><img decoding=\"async\" src=\"https:\/\/www.practicemock.com\/blog\/wp-content\/uploads\/2021\/09\/RRB_Clerk_250821-1024x128.jpg\" alt=\"RRB_Clerk_Free Mock\" class=\"wp-image-7796\"\/><\/a><\/figure>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>Jabbing (Taking a vaccine as a precaution against contracting a disease) <\/strong>children: On a COVID-19 vaccine for kids<\/h2>\n\n\n\n<h3 class=\"wp-block-heading\">As Covaxin gets closer to approval for children, data transparency is vital<\/h3>\n\n\n\n<p>As a milestone, the Subject Expert Committee\u2019s (SEC) recommendation to the Drugs Controller to grant emergency use authorisation (EUA) for Covaxin among children aged 2-18 years, is huge. If the Drugs Controller General of India (DCGI) goes ahead and grants approval, it will be the first vaccine to be administered to children in India. While one other vaccine, ZyCoV-D, has been granted EUA, it is still to be administered. Trials have started with the Serum Institute\u2019s Covovax for children, extending the timeline of any other COVID-19 vaccine for actual use in children. On the front of it, it seems like a tremendous achievement within a short period. While the data seem to have convinced the SEC that there is cause to make its considered recommendation, none of that is yet in the public domain, at the time of SEC\u2019s announcement. Bharat Biotech presented interim data from the phase II\/III trials to the DCGI, as the safety follow-up is longer in this case. One month after the two doses, an <strong>immunogenicity (relating to or producing an immune response) <\/strong>check and safety follow up are done, according to reports. The company claimed the data indicated that the vaccine used \u2014 the same product and presentation as the adult vaccine \u2014 was safe. The two-dose Covaxin was administered to 525 children 28 days apart, after it received the <strong>nod (A sign of assent) <\/strong>to conduct trials on children in May this year. A possibly unintended but welcome outcome of the pandemic is the stress on being transparent about scientific data generated in trials. Data from other vaccine trials have routinely been posted in the public <strong>realm (an area of activity)<\/strong>, not just with state regulators.<\/p>\n\n\n\n<p>Working on vaccine or drug <strong>regimens ((medicine) a systematic plan for therapy (often including diet)) <\/strong>with children is challenging on many fronts; to start with, it is not merely a case of <strong>sizing down (to gradate or arrange from larger to smaller)<\/strong> adult dosage for children. Children have distinct developmental and <strong>physiological (Of or consistent with an organism&#8217;s normal functioning) <\/strong>differences, and WHO recommends that clinical trials in children are essential to develop age-specific, <strong>empirically (Derived from experiment and observation rather than theory) <\/strong>verified therapies and interventions to determine the best possible treatments for them. Their bodies work in very different ways and they undergo many changes as they grow from infancy towards adolescence and adulthood, calling for age de-escalation studies in trials, beginning with an older age group, and working towards the youngest group. Another question experts are raising is whether the <strong>cohort (a group of individuals having a statistical factor (such as age or class membership) in common in a demographic study) <\/strong>of 525 children is large enough to wing an EUA, or if incremental numbers should be added, given the size of the target paediatric\/teen population. Many of these questions are easily addressed with publication of the data. While a recommendation is only that, it has indeed raised extraordinary expectations in the community. The DCGI, as it considers the SEC\u2019s advice, should address the concerns raised, and reinstate the issue of transparency to its rightful place as the <strong>cornerstone (The fundamental assumptions from which something is begun, developed, calculated or explained) <\/strong>of scientific temper, besides infusing confidence in the public.<\/p>\n\n\n\n<figure class=\"wp-block-image size-large\"><a href=\"https:\/\/www.practicemock.com\/exams\/banking\/ibps-rrb-office-assistant\/?refcode=2896&amp;utm_source=Blog_The+Hindu+Editorial+Vocabulary%E2%80%93+Oct+13%2C+2021%3B+Day+159_131021_RRBOAM&amp;utm_medium=Link&amp;utm_campaign=RRROAM\"><img decoding=\"async\" src=\"https:\/\/www.practicemock.com\/blog\/wp-content\/uploads\/2021\/09\/RRB_Clerk_250821-1024x128.jpg\" alt=\"RRB_Clerk_Free Mock\" class=\"wp-image-7796\"\/><\/a><\/figure>\n\n\n\n<p>Want to improve your vocabulary further?\u00a0<a href=\"https:\/\/www.practicemock.com\/blog\/vocabulary\/the-hindu-editorial-vocabulary-download-free-pdf\/\">Download the Lists of Word-Meanings of Previous Months here<\/a>.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Improve your word-power with the help of this daily recurring series where we analyze the difficult words published in prominent editorials.<\/p>\n","protected":false},"author":3,"featured_media":9581,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_uag_custom_page_level_css":"","_monsterinsights_skip_tracking":false,"_monsterinsights_sitenote_active":false,"_monsterinsights_sitenote_note":"","_monsterinsights_sitenote_category":0,"_uf_show_specific_survey":0,"_uf_disable_surveys":false,"footnotes":""},"categories":[11,25,15,5,2,31,49,47],"tags":[69],"class_list":["post-9580","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-ibps-clerk","category-ibps-po","category-ibps-rrb-clerk","category-ibps-so","category-rbi-assistant","category-sbi-clerk","category-sbi-po","category-vocabulary","tag-editorials-difficult-words-2"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v25.9 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>The Hindu Editorial Vocabulary\u2013 Oct 13, 2021; 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